Best compounded HRT providers to investigate—and approved alternatives

What makes a useful compounding comparison

Ask about the exact formulation, the clinical reason for customizing it, the dispensing pharmacy and follow-up. ACOG recommends approved menopause therapies over routine compounding when approved options meet the patient’s needs. FDA registration of a facility is not approval of a compounded product.

We distinguish providers with published compounded offerings from services included as approved-treatment alternatives. That matters because a list of clinics can otherwise imply that every provider offers the same type of medicine. Read the individual review before assuming a product is available in your state.

1. CoreAge Rx — featured partner; confirm HRT availability

Its public catalog describes online prescription care but did not list menopause estrogen or progesterone at our check. Ask for an HRT-specific offering, price and follow-up plan before paying. The first position is promotional and does not establish clinical superiority or verified HRT access.

Read the full CoreAge Rx review.

2. Winona — published compounded options

Its menu includes compounded creams and oral options alongside an estrogen patch. The catalog listed estrogen body cream with progesterone from $89 per month. Ask why a compounded preparation is appropriate, how uterine protection is handled and what the complete shipment costs.

Read the full Winona review.

3. Defy Medical — a broad hormone and compounding menu

Defy describes multiple hormone formulations and compounded combinations. We did not establish one all-inclusive menopause price from the reviewed pages. Request an itemized quote and an evidence-based explanation for each hormone, route and monitoring requirement.

Read the full Defy Medical review.

4. Evernow — a choice of visits or membership

The public page listed uninsured video visits at $150 and membership from $35 per month, with medication separate. Its menu includes approved and compounded options. Clarify billing commitment, actual product and what follow-up access is included.

Read the full Evernow review.

5. Midi Health — scheduled visits and insurance checks

The service lists FDA-approved menopause HRT and a separate compounded testosterone offering. Self-pay visits were listed at $250 initially and $150 for continued care. Verify your plan, state and medication; its Medicare and Medicaid policies need a specific check.

Read the full Midi Health review.

6. Alloy — an FDA-approved patch and delivery model

The patch page listed $100 per month, billed and shipped every three months, plus a $49 one-time consultation fee. Confirm any additional progesterone cost and the terms for changes or cancellation. This is a product price, not the price of every possible treatment plan.

Read the full Alloy review.

7. Gennev — physician visits with optional nutrition care

Gennev lists approved hormonal and nonhormonal care, with self-pay doctor visits at $250 initially and $199 for follow-up. Dietitian visits have separate fees. It is an approved-treatment comparison here; we did not verify a dedicated compounded menopause program.

Read the full Gennev review.

More published compounded offerings

Joi, Thrivelab, Inner Balance and Hone add different care models to this comparison. Their menus do not make the formulations interchangeable. Inner Balance centers on a vaginal combination marketed for systemic use; the others require checking the individual prescription. Ask why customization is needed and which approved alternatives were considered.

Additional formulations to investigate

Fem Excel describes compounded hormone care, and Alpha Hormones discusses customized Bi-Est. Ask about the exact formulation and why an approved alternative does not meet the need. The Hello Alpha review explains why a general compounding consent does not identify the approval status of every product on a provider’s menu.

Check the finished product in a mixed catalog

Interlude lists an approved generic vaginal cream alongside a separate compounded option. Elevate MD uses bioidentical language that still requires prescription-level clarification. Ask which finished medicine is proposed and why; a brand name does not establish approval status.

Before you commit

Get the exact prescription, pharmacy, total bill and follow-up arrangements in writing. Confirm whether the finished medicine is FDA-approved or compounded and why it fits your medical needs. Promotional placement, a convenient website and a positive testimonial do not establish a treatment’s suitability.

Use the appointment checklist and cost guide to finish your comparison. If the clinician advises against hormones, ask about nonhormonal options. A useful shortlist should help you ask better questions, not pressure you into a prescription.

For the practical next step, compare memberships with individual visits and review the provider-switching checklist if you already have a prescription.